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MIDAMOR (amiloride) is not an aldosterone antagonist and its effects are seen even in the absence of aldosterone.
When given with other diuretics.amiloride may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor right away if you have any of these unlikely but serious symptoms of dehydration or mineral loss. very dry mouth.extreme thirst.muscle cramps.weakness.fast heartbeat.severe dizziness.confusion.fainting.seizures.
Electrolyte Imbalance and BUN Increases. Hyponatremia and hypochloremia may occur when MIDAMOR (amiloride) is used with other diuretics and increases in BUN levels have been reported. These increases usually have accompanied vigorous fluid elimination.especially when diuretic therapy was used in seriously ill patients.such as those who had hepatic cirrhosis with ascites and metabolic alkalosis.or those with resistant edema. Therefore.when MIDAMOR (amiloride) is given with other diuretics to such patients.careful monitoring of serum electrolytes and BUN levels is important. In patients with pre-existing severe liver disease.hepatic encephalopathy.manifested by tremors.confusion.and coma.and increased jaundice.have been reported in association with diuretics.including amiloride HCl.
Store at room temperature away from moisture.heat.or freezing temperatures.
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